MS multiple sclerosis
Conditions
Interventions
None listed
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: CIS suggestive of MS as defined by the International Panel Age 18-59 years
Exclusion criteria
Exclusion criteria: Vascular, malignant or other immunological diseases at present or in the past medical history;MRI related exclusion criteria: - Claustrophobia - Foreign non MR compatible metal objects in the body - Foreign metal objects in or close to the head - Allergic reaction to contrast administration in the past (only for patients)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint of the study is MS lesion count: MR images from standard field 1.5T and high field 3T will be compared using total amount of lesions and region specific amount of lesions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints of the study: Data on cortical lesions: a double-inversion recovery (DIR) sequence is also included in the scanning protocol. This gray matter specific sequence leads to higher detection of cortical lesions. There is limited data on the quality of DIR at the various field strengths and vendors. | — |
Countries
Netherlands
Outcome results
None listed