Subfertility unfulfilled childwish.
Conditions
Interventions
In group one (*late IUI*), IUI will be performed 32-36 hours after triggering
of ovulation by hCG, which is administered when the largest follicle has
reached a diameter of 16-18 mm. In group two ("
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Couples with unexplained subfertility, mild male factor subfertility and cervical factor subfertility are eligible for IUI according to the present Dutch national guidelines, and they will be offered inclusion in this study.
Exclusion criteria
Exclusion criteria: In case of female age > 40 years old, female body mass index > 30 kg/m2, double-sided tubal pathology or severe male factor subfertility (
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter/endpoint is the ongoing pregnancy rate per IUI-MOS treatment strategy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ongoing pregnancy rate per cycle and per cause of subfertility, miscarriage rate, multiple pregnancy rate, live birth rate , adverse events, cost-effectiveness, cost-savings, budget impact resulting from a reduction of the need for additional IUI-MOS cycles and subsequent IVF-treatments, patient satisfaction and quality of life. | — |
Countries
Netherlands
Outcome results
None listed