Critical Limb Ischemia: Perfusion Computed Tomography.

Critical Limb Ischemia: Perfusion Computed Tomography. - CLIP-CT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40070

Enrollment

Registered

2013-01-04

Start date

2013-04-05

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

peripheral vascular disease and atherosclerosis of the lower limb

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - rest pain, nonhealing ulceration or gangrene of the foot, i.e. Fontaine III/IV - ankle-brachial pressure index (ABPI) 2 weeks - normal renal function (i.e. creatinine

Exclusion criteria

Exclusion criteria: - inability to give informed consent - contraindications for contrast-enhanced CT, i.e. allergic reactions to iodinated contrast agents or pregnancy - major amputation; amputation above the level of the ankle - patient participates in another study

Design outcomes

Primary

Measure	Time frame
- Signal/contrast to noise ratio of the PCT scans - PCT imaging quality scores - PCT perfusion values (blood volume, blood flow, time to peak and mean transit time) of different predefined regions of the ischemic and non-ischemic foot - Pedal arterial patency based on DSA	—

Secondary

Measure	Time frame
No secundary study parameters/outcomes	—

Countries

Netherlands

Outcome results