Serial, integrated, non-invasive mapping of electro-mechanical activation of the human heart under various pacing conditions.

Serial, integrated, non-invasive mapping of electro-mechanical activation of the human heart under various pacing conditions. - Non-invasive mapping of cardiac electro-mechanical activation patterns.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40063

Enrollment

150

Registered

2011-11-11

Start date

2011-12-08

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure heart rhythm disorder

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Humans of at least 18 years old Cardiac conduction disorder for which implantation of pacemaker is indicated Rhythm disorders for which electrophysiological examination is performed.

Exclusion criteria

Exclusion criteria: Humans younger than 18 years old. Individuals not capable of providing informed consent. Women of child bearing age and not on reliable birth control program/pregnant women.

Design outcomes

Primary

Measure	Time frame
The altered pathway of electrical and mechanical activation of the human heart and the accompanying hemodynamic response. Electrical activation: Electrical activation patterns of the human heart. Periods of conduction (pq-time, qrs-duration, qtc-time). Mechanical activation: Left ventricle (LV) contraction pattern. LV ejection fraction, stroke volume, end-diastolic pressure and volume of left ventricle. Hemodynamics of patient during study. Quality of life during study. Cardiac Electrical activation times registered simultaneously during EPS in patients suffering from arrhythmias and in individuals in whom structural heart disease is ruled out. Atrial scar in patients after ablation therapy.	—

Measure

Time frame

The altered pathway of electrical and mechanical activation of the human heart and the accompanying hemodynamic response. Electrical activation: Electrical activation patterns of the human heart. Periods of conduction (pq-time, qrs-duration, qtc-time). Mechanical activation: Left ventricle (LV) contraction pattern. LV ejection fraction, stroke volume, end-diastolic pressure and volume of left ventricle. Hemodynamics of patient during study. Quality of life during study. Cardiac Electrical activation times registered simultaneously during EPS in patients suffering from arrhythmias and in individuals in whom structural heart disease is ruled out. Atrial scar in patients after ablation therapy.

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Secondary

Measure	Time frame
(serious) adverse events	—

Countries

Netherlands

Outcome results