premature ovarian Faillure
Conditions
Interventions
One group will undergo a regular hysterectomy only (either vaginal, abdominal
or laparoscopically) (=control group). The other group will receive a regular
hysterectomy including a bilateral salping
Sponsors
TweeSteden ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Otherwise healthy women undergoing hysterectomy for benign indications (eg. bleeding disorder, fibroids, adenomyosis) without a family history of ovarian / tubal / breast cancer, will be asked to participate.
Exclusion criteria
Exclusion criteria: Family history of cancer, history of any form of cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| concentration AMH, FSH and oestradiol pre- and six months postoperatively. Does a salpingectomy during hysterectomy for benign indications change hormonal status significantly, indicating a shift towards menopausal status? | — |
Secondary
| Measure | Time frame |
|---|---|
| What is the incidence of premalignancies in Fallopian tubes from women not at hereditary high risk to develop serous carcinomas? Is there a difference in quality of life (QoL) between the two groups? | — |
Countries
Netherlands
Outcome results
None listed