depressive disorder
Conditions
Interventions
Short-term continuation PCT (C-PCT) consist of 8 sessions that is offered as
sequential treatment after response to A-CT. CT is directed at the
identification of maladaptive cognitions and the devel
Sponsors
Arkin (Amsterdam)
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Two or more previous depressive episodes, 2. In remission according to DSM-IV criteria, 3. A current score of
Exclusion criteria
Exclusion criteria: 1. Current mania or hypomania or a history of bipolar illness, 2. Any psychotic disorder (current and previous), 3. Alcohol or drug misuse, 4. Predominant anxiety disorder, 5. Insufficient mastering of the Dutch language.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure is the cumulative proportion of relapses/recurrences in a survival-analysis over a follow-up period of 15 months after the start of the preventive therapy as measured with the *Structural Interview for DSM-IV (SCID) using the Longitudinal Interval Follow-up Evaluation (LIFE). | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome variables are: 1. the severity of depressive symptoms as measured with the 'Inventory of Depression Symptomatology' (IDS-SR), and the *Hamilton Depression Rating Scale* (HDRS), 2. well-being, quality of life as measured with (EQ-5D), 3. social and interpersonal functioning as measured with the *Inventory of Interpersonal Problems* (IIP), 4. coping styles as measured with the *Utrecht Coping List* (UCL) 5. experienced negative life events as measured with the 'Brugha Questionaire' (Brugha) 6. personality disorder symptomatology as measured with the *Personality diagnostic questionnaire-revised* (PDQ-R) 7. level of psychological mindfulness as measured with the *Psychological Mindfulness Scale* (PMS) 8. sense of mastery as measured with the *Mastery scale* 9. consumption of mental health care and degree of work absence as measured with the *Trimbos/iMTA questionnaire for Costs associated with Psychiatric Illness* (TIC P) 10. identification of potential mediators and mechanisms of change using: a. coping styles as measured with the subscales *Active coping* and *Avoidance* of the *Utrecht Coping List* (UCL), b. social support as measured with the *Sociale Steun Lijst * Interacties* (SSL-I), c. acceptance and action as measured with the *Acceptance and Action Questionnaire* (AAQ), d. assessment of outcome as measured with the *Outcome Rating Scale* (ORS), e. the client*s perspective of the alliance with the therapist as measured with the *Session Rating Scale* (SRS), f. the severity of depressive symptoms as measured with the *Beck Depression Inventory* (BDI), g. working alliance as measured with the *Werk Alliantie Vragenlijst* (WAV-12), h. the intensity of dysfunctional attitudes as measured with the *Dysfunctional Attitude Scale* (DAS-17), i. the need for affiliation as measured with the *Affiliatie Lijst*, j. experienced daily stressors as measured with the *Daily Hassles Questionnaire*, k. positive and negative a | — |
Countries
Netherlands
Outcome results
None listed