The effect of exercise on the prevention of endothelial ischemia-reperfusion injury

The effect of exercise on the prevention of endothelial ischemia-reperfusion injury - Exercise-endothelial IR

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON40007

Enrollment

Registered

2013-03-05

Start date

2013-09-19

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease

Interventions

A bout of traditional moderate-intensity exercise and high-intensity interval exercise

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Healthy volunteers >18 years - Written informed consent

Exclusion criteria

Exclusion criteria: -Presence of an absolute contra-indication for the performance of exercise (see also SOP Inspanningstest Department of Physiology):

Design outcomes

Primary

Measure	Time frame
Change in endothelial function (measured with flow mediated dilation) after ischaemia reperfusion injury (induced by 20 minutes ischemia) with and without precedence of an acute bout of moderate-intensity endurance or (isocaloric) high-intensity interval exercise.	—

Secondary

Measure	Time frame
nitrite/nitrate in plasma	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)