agressieregulatie problematiek aggression anger
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: For participants with impulsive aggression, the following inclusion criteria: - Soldiers and veterans (men) who participated in a military deployment (minimum 4 months) - Age between 18 and 50 years - Presence of problems with aggression as evidenced by either (I): the A1 or A2 criterion of the research diagnostic criteria for impulsive aggression "(Coccaro, 2012), or (II) evidence for problems with pent-up anger as revealed by answers to the screening questionnaire. - Written informed consent; For control participants, the following inclusion criteria: - Healthy men - Age between 18 and 50 years - Written informed consent - No (current) DSM-IV Axis-I disorder - No evidence of problems with aggression
Exclusion criteria
Exclusion criteria: - Alcohol / substance abuse and / or dependence - Severe neurological diseases (eg Parkinson's disease, stroke, MS);Exclusion for MRI procedure: - Claustrophobia, pacemaker (or other implants), or metal objects in the body causing an MRI scan is not possible. - Current use of psychotropic drugs (benzodiazepines, antidepressants, antipsychotics, anticonvulsants)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in amygdala and prefrontal cortex activity, differences in startle response, differences in blood parameters as neuropeptide Y, vasopressin and testosterone, differences in performance on neuropsychological tasks between veterans with aggression regulation problems and healthy control participants. | — |
Secondary
| Measure | Time frame |
|---|---|
| n.a. | — |
Countries
Netherlands
Outcome results
None listed