affective instabilitty borderline personality disorder
Conditions
Interventions
None listed
Sponsors
Universiteit Leiden
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Participants with BPD 1) All BPD participants in this study will be recruited from the participants in the BPD treatment study (P12.227). The diagnosis of BPD will be confirmed by a structured diagnostic interview already assessed in that study. The same inclusion criteria will be adopted, except for additional fMRI requirements (see the protocol for details). 2) After being fully informed about the study and the risks of participation informed consent should be signed.;Healthy participants 1) Participants are able to understand the given information 2) After being fully informed about the study and the risks of participation informed consent should be signed 3) Participants are in excellent mental and physical condition 4) Age: > 18 yrs,
Exclusion criteria
Exclusion criteria: Participants with BPD 1) Alcohol or drugs abuse 2) The use of benzodiazepines more than the equivalent of 20 mg of oxazepam or any antipsychotic medication (Stable use of SSRI*s is allowed) 3) Metal implants, surgical clips, pacemakers, and left-handedness.;Healthy participants 1) History of psychiatric problems by the MINI 2) Somatic illnesses 3) Alcohol or drug dependence by the MINI 4) Regular medications 5) Metal implants, surgical clips, pacemakers, and left-handedness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Behavioural measures: self-report ratings on state self-esteem and mood states during the tasks (evaluative social feedback and script-driven emotional imagination. Imaging): Blood-Oxygen-Level Dependent (BOLD) response during these tasks; BOLD response during rest and after the evaluative social feedback task (functional connectivity). | — |
Secondary
| Measure | Time frame |
|---|---|
| None | — |
Countries
Netherlands
Outcome results
None listed