Optical techniques in diagnosis and management of premalignant and malignant laryngeal and pharyngeal lesions.

Optical techniques in diagnosis and management of premalignant and malignant laryngeal and pharyngeal lesions. - Optical techniques in diagnosis of (pre)malignant laryngopharyngeal lesions

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39924

Enrollment

350

Registered

2014-11-20

Start date

2015-03-06

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

premaligne en maligne tumoren van de larynx en farynx head and neck cancer laryngeal/pharyngeal cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: All patients presented with laryngeal or pharyngeal tumours suspect for malignancy or proven to be malignant in Radboud University Nijmegen Medical Centre or Medical Centre Leeuwarden are eligible for inclusion.

Exclusion criteria

Exclusion criteria: Age younger than 18 years old Inability to undergo generals anaesthesia Metal incompetence

Design outcomes

Primary

Measure	Time frame
The main study parameters are the assessment of the extend of mucosal pathology by video recordings of High Definition videolaryngoscopy compared with that by rigid direct laryngoscopy using a standard format for judgement of tumour extension.	—

Secondary

Measure	Time frame
Secondary study parameters are: date of first contact, standardized judgment of fiberoptic and videolaryngoscopy compared to HD videolaryngoscopy and direct laryngoscopy, standardized judgment of first videolaryngoscopy 2-3 weeks earlier and comparison with study videolaryngoscopy, date of laryngoscopy in general anaesthesia, date of start of treatment and time till start of treatment, follow up time, recurrence rate and date of recurrence, patients quality of life and voice handicap, and costs of diagnostic route.	—

Measure

Time frame

Secondary study parameters are: date of first contact, standardized judgment of fiberoptic and videolaryngoscopy compared to HD videolaryngoscopy and direct laryngoscopy, standardized judgment of first videolaryngoscopy 2-3 weeks earlier and comparison with study videolaryngoscopy, date of laryngoscopy in general anaesthesia, date of start of treatment and time till start of treatment, follow up time, recurrence rate and date of recurrence, patients quality of life and voice handicap, and costs of diagnostic route.

—

Countries

Netherlands

Outcome results