Correlates of the COPD Assessment Test (CAT) after stratification for GOLD stages and its response to pulmonary rehabilitation in patients with moderate to very severe COPD.

Correlates of the COPD Assessment Test (CAT) after stratification for GOLD stages and its response to pulmonary rehabilitation in patients with moderate to very severe COPD. - Correlates of CAT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39909

Enrollment

850

Registered

2012-04-23

Start date

2012-04-25

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD emphysema or chronic bronchitis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Age 40-85 years 2. A diagnosis of COPD according to GOLD guidelines only applicable for COPD patients 3. Referral for assessment and pulmonary rehabilitation in Ciro+ by a chest physician only applicable for tertiary care patients. 4. Healthy, as judged by the investigator and determined by medical history and physical examination and post-bronchodilator FEV1/FVC * 70 only applicable for healthy controls

Exclusion criteria

Exclusion criteria: 1. For healthy controls, primary, secondary and tertiary care patients: a history of asthma, kung cancer, sarcoidosis, tuberculosis, lung fibrosis, or any other significant respiratory disease; having undergone lung surgery (e.g. lung volume reduction, lung transplantation); any clinically relevant disease which in the opinion of the investigator may influence the results of the study 2. For primary, secondary and tertiary care patients only: moderate or severe exacerbation or pneumonia requiring systemic corticosteroids, antibiotics or hospitalisation during the last 4 weeks 3. For health controls only: COPD, chronic heart failure 4. Treatment by respiratory physician or tertiary care in primary care COPD patients 5. Treatment in tertiary care setting for secondary care COPD patients 6. Participation in an interventional clinical study during the past three months (for primary and secondary care patients).

Design outcomes

Primary

Measure	Time frame
The main study parameters are the CAT scores of the COPD patients and the healthy controls. With the CAT scores we can examine the absolute and percent difference between COPD patients based on severity of their COPD. Also the absolute and percent difference between COPD patients and healthy controls shall be examined. For the tertiary care patients is the change in CAT score before and after rehabilitation important. CAT scores shall also be correlated with existing HRQL questionnaires, co-morbidity, and other potential confounders.	—

Measure

Time frame

The main study parameters are the CAT scores of the COPD patients and the healthy controls. With the CAT scores we can examine the absolute and percent difference between COPD patients based on severity of their COPD. Also the absolute and percent difference between COPD patients and healthy controls shall be examined. For the tertiary care patients is the change in CAT score before and after rehabilitation important. CAT scores shall also be correlated with existing HRQL questionnaires, co-morbidity, and other potential confounders.

—

Secondary

Measure	Time frame
not applicable.	—

Countries

Netherlands

Outcome results