gender dysphoria gender identity disorder
Conditions
Interventions
None listed
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
2 Years to 99 Years
Inclusion criteria
Inclusion criteria: Children • Patients - DSM-IV-TR diagnosis Gender Identity Disorder - 1st measurement: puberty must not yet been reached. Children have to be maximally in Tanner stage 1. - 2nd measurement: children have to have entered puberty yet. They have to be at least in Tanner stage 2-3. - Right-handedness • Controls - 1st measurement: puberty must not yet been reached. Children have to be maximally in Tanner stage 1. - 2nd measurement: children have to have entered puberty yet. They have to be at least in Tanner stage 2-3. - Right-handedness;Adolescents • Patients - DSM-IV-TR diagnosis Gender Identity Disorder - 1st measurement: patients receive a GnRH-agonist in order to suppress puberty. - 2nd measurement: patients receive cross-sex hormone treatment - Right-handedness;• Controls - Adolescents match in terms of age, sex and educational level with the patient group - Right-handedness Adults • Patients - DSM-IV-TR diagnosis Gender Identity Disorder - two measurements: 1) oto-acoustic emissions (OAE), 2) 2D:4D ratios
Exclusion criteria
Exclusion criteria: all subjects: - Mental retardation (IQ
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the Blood oxygen level dependent (BOLD) response in the fMRI tasks. In the adult participants, the main study parameters are the OAEs and the 2D:4D ratios. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures are the neuropsychological test parameters, the otoacoustic emission data, self-report data, and hormone level assessments. | — |
Countries
Netherlands
Outcome results
None listed