n.a.
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
12 Years to 99 Years
Inclusion criteria
Inclusion criteria: epilepsy patients with implanted electrodes for diagnostic purposes age 12 years and older (no upper limit) no metal objects in or around the body (braces, pacemaker, metal fragments) ;(Amendement september 2012): a vagal nerve stimulator is permitted
Exclusion criteria
Exclusion criteria: x
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The results are expected to lead up to the development of a first implantable prototype for paralyzed patients. The key questions that will be addressed are: 1) which features of brainsignals obtained from cortical surface electrodes can be used for BCI, 2) which brain areas produce the best results for BCI cursor control, 3) can subjects use multiple brain-areas to control a cursor in multiple directions 4) can target areas be pre-localized accurately with fMRI (amendment 12 jan 2012:) 5) are the signals obtained with a prototype implantable amplifier adequate for BCI. (amendement september 2012): 2) which brain areas produce the best results for BCI control, 3) can target areas be pre-localized accurately with fMRI, 4) are the signals obtained with a prototype implantable amplifier adequate for BCI. | — |
Secondary
| Measure | Time frame |
|---|---|
| (amendment 12 jan 2012) A prototype implantable EEG amplifier will be tested outside the body in three patients. The outcome measure is quality of the EEG signal (signal-to-noise ratio) and actual BCI performance with that signal, as compared to those measure obtained with the clinical EEG system (measurements are performed in parallel) (amendment september 2012) A prototype implantable EEG amplifier will be tested outside the body. The outcome measure is quality of the EEG signal (signal-to-noise ratio) and actual BCI performance with that signal, as compared to those measure obtained with the clinical EEG system (measurements are performed in parallel). In addition, we would like to determine the optimal settings of the device for accurate BCI control. | — |
Countries
Netherlands
Outcome results
None listed