Study of the genetic causes of disorders of the aorta, arteries and cardiac valves

Study of the genetic causes of disorders of the aorta, arteries and cardiac valves - Aorta

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39758

Enrollment

500

Registered

2014-03-18

Start date

2014-06-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aortic dilatation heart valve malformation

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria 1. Patients and familymembers with thoracic aortic aneurysm and dissection 2. Patients and familymembers with Marfan syndrome and related conditions 3. Patients and familymembers with bicuspid aortic valve, specifically if associated with aortic aneurysm or history of sudden death or aortic dissection 4. Patients and family members with arterial aneurysms and/or valve abnormalities No restriction for age or sex.

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
Identification of the genetic factors underlying thoracic aortic aneurysms or modify the phenotypic severity.	—

Secondary

Measure	Time frame
nvt	—

Countries

Netherlands

Outcome results