Stress reactivity in psychosis: the association between traumatic events, genetic vulnerability and psychotic reactivity to stress

Stress reactivity in psychosis: the association between traumatic events, genetic vulnerability and psychotic reactivity to stress - STRIP2

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39714

Enrollment

120

Registered

2011-09-14

Start date

2011-10-10

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psychosis schizophrenia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) aged between 18-60 2) sufficient command of the Dutch language 3) no intellectual impairment (IQ>80) 4) Additional inclusion criteria for the 22q11DS group: A confirmed deletion at chromosome 22q11

Exclusion criteria

Exclusion criteria: 1) Current use of psychotropic medication (non-patients only) 2) Current cannabis dependence 3) Current alcohol dependence 5) Severe endocrine, cardiovascular or brain disease

Design outcomes

Primary

Measure	Time frame
Psychotic experiences as measured in daily life (PsyMate) Stress as measured in daily life (PsyMate)	—

Secondary

Measure	Time frame
Cortisol niveaus as measured in daily life (saliva samples) The amount of experienced traumatic events as measured by questionnaires and interviews Genetic risk for psychosis (DNA)	—

Countries

Netherlands

Outcome results