Urinary NTproBNP to reduce eye examinations in preterm infants

Urinary NTproBNP to reduce eye examinations in preterm infants - REDEXAM study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39687

Enrollment

100

Registered

2012-07-04

Start date

2012-11-06

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retinopathy of prematurity

Interventions

None listed

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: Gestational age

Exclusion criteria

Exclusion criteria: - Lack of parental consent - infant likely to die soon - infant scheduled for early transfer to another institution without reliable ophthalmologic examinations (not applicable to the Netherlands)

Design outcomes

Primary

Measure	Time frame
100% negative predictive cut-off values for urinary NTproBNP concentrations normalized to creatinine at 2 and 4 weeks of life for threshold ROP (stage II+ or more in zone 2 or 3, or any ROP in zone 1)	—

Secondary

Measure	Time frame
100% negative predictive cut-off values for urinary NTproBNP concentrations normalized to creatinine at 2 and 4 weeks of life for ROP intervention (laser-/cryo surgery ) 100% negative predictive cut-off values for urinary NTproBNP concentrations at 2 and 4 weeks of life without normalization to creatinine for threshold ROP (stage II+ or more in zone 2 or 3, or any ROP in zone 1) 100% negative predictive cut-off values for urinary NTproBNP concentrations at 2 and 4 weeks of life without normalization to creatinine for ROP intervention (laser/cryo surgery)	—

Measure

Time frame

100% negative predictive cut-off values for urinary NTproBNP concentrations normalized to creatinine at 2 and 4 weeks of life for ROP intervention (laser-/cryo surgery ) 100% negative predictive cut-off values for urinary NTproBNP concentrations at 2 and 4 weeks of life without normalization to creatinine for threshold ROP (stage II+ or more in zone 2 or 3, or any ROP in zone 1) 100% negative predictive cut-off values for urinary NTproBNP concentrations at 2 and 4 weeks of life without normalization to creatinine for ROP intervention (laser/cryo surgery)

—

Countries

Netherlands

Outcome results