Identification of proteins and genes involved in proliferative diabetic retinopathy

Identification of proteins and genes involved in proliferative diabetic retinopathy - Factors involved in PDR

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39671

Enrollment

Registered

2014-02-27

Start date

2014-08-13

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

proliferative diabetic retinopathy. Vessel newgrowth in retina in diabetes

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with proliferative diabetic retinopathy who need a vitrectomy. Controlgroup: Patients (without diabetes mellitus) with a macular hole, a macular pucker or vitreous floaters who need a vitrectomy

Exclusion criteria

Exclusion criteria: No informed consent Age >18 years Legal incapacity In the control group: No informed consent Age >18 years Legal incapacity Diabetes mellitus

Design outcomes

Primary

Measure	Time frame
Primary study parameter is presence of to-be-detremined proteins in the vitreous of patients with PDR compared with healthy persons. Furthermore, using microarray analysis, RNA transcripts will be determined that are increased in patients with PDR compared to non-diabetic patients.	—

Countries

Netherlands

Outcome results