autism spectrum disorder and obsessive compulsive disorder
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: (1) Aged 8-12 years (2) For Autism Spectrum Disorder: DSM-IV-TR diagnosis of ASD (3) For Obsessive Compulsive Disorder: DSM-IV-TR diagnosis of OCD (4) For Controls: no psychiatric diagnosis and no history of psychiatric illness in first or second-degree familiy members. (5) Signed informed consent
Exclusion criteria
Exclusion criteria: (1) Mental retardation (IQ
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Secundary endpoints are (1) genotypes of candidate genes and (2) lab assesments of various proteins in blood plasma. | — |
Primary
| Measure | Time frame |
|---|---|
| Primary endpoints are phenotypic meassures of compulsivity, impulsivity and addiction, and functional and connectivity measures (fMRI, DTI-MR) of striatal and prefrontal regions. | — |
Countries
Netherlands
Outcome results
None listed