Consequences and Risk factors Of congenital CytomegalovirUS infection

Consequences and Risk factors Of congenital CytomegalovirUS infection - CROCUS-study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39637

Enrollment

25000

Registered

2012-07-25

Start date

2012-10-15

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital CMV infection congenital cytomegalovirus infection

Interventions

None listed

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: - Children who underwent neonatal screening and of whom the dried blood spot is stored for 5 years. (Phase 1, n

Exclusion criteria

Exclusion criteria: - Children who did not participate in neonatal screening - Chidren whose dried blood spots are not stored for 5 years - No informed consent of parents for testing the dried blood spots or participation in the study

Design outcomes

Primary

Measure	Time frame
Hearing function at the age of 5 to 6 years	—

Secondary

Measure	Time frame
- Neonatal hearing function and cognitive function, motor function, visual function and growth during childhood (0 to 6 years) - Quality of life of the children (at the age of 5 to 6 years) and of their parents. - Viral load of CMV in the dried blood spots. Additional study: - Predictive factors for the outcome of congenital CMV infection.	—

Countries

Netherlands

Outcome results