appearance of endometrial tissue outside the womb. Endometriosis
Conditions
Interventions
None listed
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - at least one patent tube (at HSG or laparoscopy with chromopertubation) - regular menstrual cycle (28 +/- 3 days) - cases: presence of endometriosis with uni- or bilateral ovarian endometrioma. - controls: no presence of endometriosis confirmed by laparoscopy - signed informed consent form - negative pregnancy test
Exclusion criteria
Exclusion criteria: - hormone therapy - contra indications for MRI - in controls: laparoscopy > 3 years ago - presence of any malignancy - frozen pelvis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of blood-stained peritoneal fluid measured by TVUS and MRI during menses and during cycleday 20-22 in women with endometriosis versus healthy controls. | — |
Secondary
| Measure | Time frame |
|---|---|
| - the location and the resorption of blood stained peritoneal fluid. - the changes in volume and aspect of endometrial cysts during the menstrual cycle. - The molecular- biological relationship between tissue of the endometrial cyste and the endometrium. - Signal intensity and thickness of the junctional zone in endometriosis patients and controls. - Apparent diffusion coefficient (ADC) in endometrial cysts, myometrium and junctional zone. | — |
Countries
Netherlands
Outcome results
None listed