Biomarkers as predictors of wound healing after lower leg amputations in patients with severe peripheral arterial disease.

Biomarkers as predictors of wound healing after lower leg amputations in patients with severe peripheral arterial disease. - AmpuBase

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39615

Enrollment

Registered

2013-03-20

Start date

2014-09-29

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Verbeteren van kwaliteit van leven critical ischemia Intermittent claudication

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients older than 18 years who undergo amputation of the lower leg

Exclusion criteria

Exclusion criteria: Mental incompetence and amputation due malignancy in the leg

Design outcomes

Primary

Measure	Time frame
Those patients within 100 days are back for a re-intervention and / or a secondary amputation will be considered as bad recovering patients. Patients who have a good recovery are the patients who do not re-intervention and or secondary amputation need within 100 days. These two groups will be compared with each other and with a third group of healthy controls. By comparing the blood and tissue from different groups biomakers wil be identified that can predict the chance of cure of an amputation wound.	—

Measure

Time frame

Those patients within 100 days are back for a re-intervention and / or a secondary amputation will be considered as bad recovering patients. Patients who have a good recovery are the patients who do not re-intervention and or secondary amputation need within 100 days. These two groups will be compared with each other and with a third group of healthy controls. By comparing the blood and tissue from different groups biomakers wil be identified that can predict the chance of cure of an amputation wound.

—

Secondary

Measure	Time frame
.	—

Countries

Netherlands

Outcome results