Cerebrovasculair Accident CVA Stroke
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: regarding the primary objective: 1) an upper limb deficit, i.e. a NIHSS score of 1-4 in the second week post stroke; 2) a first-ever ischemic lesion in the territory of the MCA, verified by CT and/or MRI scan; 3) age between 40 and 75 years; 3) written or oral informed consent; 4) be able to sit for 30 seconds without support. Regarding the secondary objective: patients > 1 year post stroke with a motor deficit of the upper extremity NHSS *1; healthy volunteers within expected age range of stroke survivors, i.e. 40-75 years.
Exclusion criteria
Exclusion criteria: 1) a pacemaker or other metallic implants; 2) upper extremity orthopaedic limitations; 3) not being able to communicate i.e.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| primary: cortico- muscular coherence, i.e. the concordance between brain and muscle activity at different brain areas, expressed as a fraction | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary: clinical outcome as measured by the Action Research Arm Test (ARAT), Motricity Index (MI) of arm and leg, Fugl-Meyer for the arm (FM-arm), Erasmus modification of the Nottingham Sensory Assessment (EmNSA), Letter Cancellation Task (LCT), Nine Hole Peg test (NHPT), a structured participant interview of real arm use using the Motor Activity Log (MAL), Stroke Impact Scale (SIS version 3.0) and Nottingham Extended ADL (NEADL). | — |
Countries
Netherlands
Outcome results
None listed