Determination of minimum and non-provoking doses of soy protein in soy allergic individuals

Determination of minimum and non-provoking doses of soy protein in soy allergic individuals - Determination of minimum and non provoking doses of soy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON39595

Enrollment

Registered

2013-08-19

Start date

2014-01-28

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

food allergy soy allergy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) Convincing clinical history of a Type I allergic reaction caused by eating soybeans or soy flour 2) Positive skin prick test to the extract of soy flour used to make the oral challenges AND positive specific immunoglobulin E (IgE) to soy (CAP-RAST, Pharmacia Uppsala, Sweden). Subjects should also be skin prick tested with a commercial soy extract. 3) Adults (18-70 years)

Exclusion criteria

Exclusion criteria: 1) Subjects with allergy to wheat 2) Pregnancy

Design outcomes

Primary

Measure	Time frame
To determine minimum and non-provoking doses of soy protein (in mg) for soy allergic individuals.	—

Secondary

Measure	Time frame
To determine the relevant allergens of soy in soy allergy and to determine the relation between allergen recognition pattern and severity of the allergy.	—

Countries

Netherlands

Outcome results