Macroscopic and microscopic changes of a locally advanced rectal tumour during radiotherapy: assessment using anatomical, functional and cinematic MRI.

Macroscopic and microscopic changes of a locally advanced rectal tumour during radiotherapy: assessment using anatomical, functional and cinematic MRI. - Imaging in locally advanced rectal cancer.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39583

Enrollment

Registered

2010-05-20

Start date

2011-04-29

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal carcinoma rectal cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Rectal tumor

Exclusion criteria

Exclusion criteria: - Patients who meet exclusion criteria for MRI at 3T - Patients with inflammable bowel disease or diverticulitis - Patients with history of pelvic surgery - Patients with history of pelvic tumours

Design outcomes

Primary

Measure	Time frame
Observational study to analyse rectal tumour regression and tumour movement during long course pre-operative RCT for LARC in order to develop a dose escalation strategy for rectal cancer. Besides this first endpoint it is also an explorative study to analyse the feasibility to apply anatomical and functional MRI during RCT in the evaluation of treatment response.	—

Secondary

Measure	Time frame
Not applicable.	—

Countries

Netherlands

Outcome results