acute myocardial infarction athlete's hart
Conditions
Interventions
Remote ischemic preconditioning, induced by four 5 min cycles of upper limb
ischemia interspaced with 5 min of reperfusion (200 mm Hg) or a control
procedure with low-pressure cuff inflation (10 mm
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Informed consent Healthy Age between 18 and 65 years Endurance-trained (two or more training sessions per week)
Exclusion criteria
Exclusion criteria: Not applicable
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum concentration of cardiac troponins (T and I) at baseline, pre-exercise and 0, 2, 4, 6, 8, 10 hours post-exercise. Indices of cardiac function measured at baseline and immediately post-exercise. | — |
Secondary
| Measure | Time frame |
|---|---|
| Other cardiac markers: e.g. NT-proBNP Various molecular forms of cardiac troponin T and I Markers to correct variation in renal function during exercise: e.g. creatinin, cystatin C, albumin, hematocrit. Inflammatory markers: e.g. CRP Oxidative status: e.g. thiobarbituric acid reactive substances (TBARS), trolox equivalent anti-oxidant capacity (TEAC), erythrocyte susceptibility to in vitro peroxidation. Heart rate Duration of 30km-run Baseline blood pressure | — |
Countries
Netherlands
Outcome results
None listed