Standard versus transepithelial corneal crosslinking for treatment of progressive keratoconus

Standard versus transepithelial corneal crosslinking for treatment of progressive keratoconus - Transepithelial corneal crosslinking

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON39491

Enrollment

Registered

2011-04-20

Start date

2011-05-30

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

corneal deformation Keratoconus

Interventions

CXL is performed on all patients included in the study. Patients will be divided at random into two groups. Group 1 will undergo standard CXL treatment with the initial step of epithelial removal pr

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patient age of >= 18 years, documented progressive KC (by Pentacam and/or corneal topography imaging), a clear central cornea, minimal corneal thickness of at the thinnest corneal location (Pentacam imaging), minimal Snellen corrected distance visual acuity of >= 0.4.

Exclusion criteria

Exclusion criteria: Patient age less than 18 years, stable keratometry values over time, presence of corneal scar(s)

Design outcomes

Primary

Measure	Time frame
The main study parameter is the keratometry outcome over a period of 1 year, which is measured by corneal topography and Pentacam imaging.	—

Secondary

Measure	Time frame
The secondary objective is the incidence of epithelial healing problems after treatment.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)