Obsessive Compulsive Disorder obsessive neurosis
Conditions
Interventions
The intervention consists of either 15 relevant checking trials, 15 irrelevant
checking trials or 15 relevant checking trials with perceptually modified
stimuli at post-test
Sponsors
Universiteit Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients will be included when they have a DSM-IV diagnosis of Obsessive Compulsive Disorder or another anxiety disorder diagnosis. Patients are allowed to use SSRI drugs, but not benzodiazepines because these have a negative effect on ones reaction speed. Healthy controls will be age/education matched with the patients included in the study.
Exclusion criteria
Exclusion criteria: Subjects will be excluded from the study if they have color vision deficiency (color blindness); if they are insufficiently proficient in the Dutch language; if they are addicted to alcohol or drugs; if they are under 18 years of age; and/or if they present with symptoms from the psychotic spectrum. Patients who use benzodiazepine drugs will be excluded. Healthy controls will also be excluded when they have any current psychiatric disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are check duration at pre-test and post-test, and reaction times on the RIR task, as well as the measures at pre-test and post-test on the checking task, and the difference between pre- and post-test, in participants* ratings of memory vividness, memory detail and confidence in memory. The final three measures will be determined from VAS-scale indications. | — |
Secondary
| Measure | Time frame |
|---|---|
| In order to test whether between-group differences are specifically related to OCD and not to patients being more anxious/depressed in general, we will measure depression (BDI), anxiety (BAI) and OCD (OCI-R and Y-BOCS) severity scores. Patients* medication will be recorded before the beginning of the experiment. While it is not expected that medication has an influence on the experimental results, recording the information leaves the option open to control for medication if need be. | — |
Countries
Netherlands
Outcome results
None listed