part a) Follow-up brain imaging study in obsessive-compulsive disorder;part b) Frontal-striatal and limbic circuits in Tourette and OCD, a brain imaging study

part a) Follow-up brain imaging study in obsessive-compulsive disorder;part b) Frontal-striatal and limbic circuits in Tourette and OCD, a brain imaging study - part a) Follow-up brain imaging study in OCD;part b) Brain imaging study in Tourette and OCD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39420

Enrollment

Registered

2008-08-11

Start date

2009-01-01

Completion date

Unknown

Last updated

2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obsessive-compulsive disorder Tourette

Interventions

Repetitive transcranial magnetic stimulation (rTMS) will be used to temporarily enhance the excitability of the dorsal prefrontal cortex in patients and, in contrast, to temporarily reduce dorsal re

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Obsessive-compulsive disorder Tourette 18-65 years old

Exclusion criteria

Exclusion criteria: psychotropic medication epilepsy metal in body pregnancy psychotic symptoms major somatic disorders severe claustrophobia

Design outcomes

Primary

Measure	Time frame
BOLD response during response inhibition task	—

Secondary

Measure	Time frame
- Glutamate concentration in dorsal ACC (MRS) - Fractional Anisotropy (DTI) - cortical thickness preSMA (T1 MRI) - BOLD response at rest	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)