Social cognition in children treated for a brain tumour: A comparative prospective international multi-centre study

Social cognition in children treated for a brain tumour: A comparative prospective international multi-centre study - Social cognition in paediatric brain tumour patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39404

Enrollment

Registered

2011-04-13

Start date

2011-04-18

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neuropsychologische stoornissen CNS Neoplasm

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Brain tumour patients: 1) Aged 5-12 years at first assessment 2) Newly diagnosed brain tumour patients that have not yet received adjuvant therapy 3) Stable medical condition;Healthy controls: 1) Aged 5-12 years at first assessment ;CF patients: 1) Aged 5-12 years at first assessment 2) Stable medical condition

Exclusion criteria

Exclusion criteria: Brain tumour patients: 1) Diagnosed with a disorder of the autistic spectrum, not related to the tumour (Autism, Asperger*s Syndrome or Pervasive Developmental Disorder not otherwise specified). 2) History of other brain disease or neurological condition interfering with normal development. 3) No native Dutch speaker 4) Severe sensory handicaps and/or behavioural problems interfering with reliable neuropsychological assessment 5) IQ below 70 6) Poor prognosis and life expectancy less than 1 year.;Healthy controls: 1) Diagnosed with a disorder of the autistic spectrum (Autism, Asperger*s Syndrome or Pervasive Developmental Disorder not otherwise specified). 2) History of other brain disease or neurological condition interfering with normal development. 3) No native Dutch speaker 4) Severe sensory handicaps and/or behavioural problems interfering with reliable neuropsychological assessment. 5) IQ below 70;CF patients: 1) Diagnosed with a disorder of the autistic spectrum (Autism, Asperger*s Syndrome or Pervasive Developmental Disorder not otherwise specified). 2) History of other brain disease or neurological condition interfering with normal development. 3) No native Dutch speaker 4) Severe sensory handicaps and/or behavioural problems interfering with reliable neuropsychological assessment. 5) IQ below 70

Design outcomes

Primary

Measure	Time frame
Change in performance on tests of social cognition from time 1 to time 2.	—

Secondary

Measure	Time frame
1) Change in reports of social and emotional functioning of patients themselves, parents and teachers from time 1 to time 2. 2) Influence of Individual medical characteristics on the change in performance on tests of social cognition from time 1 to time 2. 3) Influence of Socio-economical status (parental education and occupation) on the change in performance on tests of social cognition from time 1 to time 2 4) Influence of Intelligence level and Executive Functions on the change in performance on tests of social cognition from time 1 to time 2.	—

Measure

Time frame

1) Change in reports of social and emotional functioning of patients themselves, parents and teachers from time 1 to time 2. 2) Influence of Individual medical characteristics on the change in performance on tests of social cognition from time 1 to time 2. 3) Influence of Socio-economical status (parental education and occupation) on the change in performance on tests of social cognition from time 1 to time 2 4) Influence of Intelligence level and Executive Functions on the change in performance on tests of social cognition from time 1 to time 2.

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Countries

Netherlands

Outcome results