arthritis of the knee gonarthritis
Conditions
Interventions
first 6 weeks of placebo or combination of green lipped mussel, curcumin and
ribus nigrum (supplement Synofit) supplemantation after that a wash-out
interval of 6 weeks followed by 6 weeks of either
Sponsors
Ziekenhuisvoorzieningen Gelderse Vallei
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - patients with clinical and radiological osteoarthritis of the knee (uni-and bilateral) - voluntary participation
Exclusion criteria
Exclusion criteria: - patients with arthritis of the knee with an operation indication - comborbidity: rheumatoid arthritis, polyarthritis - patient who use medication as: methotrexate and systemic corticosteroids - arthritis of the hip at the same side (referred pain) - patients who use analgetica stronger than NSAIDs (f.e. Tramadol, Opioids) - pregnancy - allergic or sensitivity for ingredients of Synofit - patient who use Synofit before
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| during the first consultation and at 6, 12 and 18 weeks, the pain scores by the VAS-scale and quality of life by the KOOS-score are taken. Another outcome is extra pain medication within one of the study periods of suppletion. | — |
Secondary
| Measure | Time frame |
|---|---|
| side-effects compliance | — |
Countries
Netherlands
Outcome results
None listed