Autism Autism Spectrum Disorders
Conditions
Interventions
Children with autism and their parents will all (eventually) receive PRT. The
duration and amount of treatment sessions is equal for all participants, i.e.,
children and their parents will go to the
Sponsors
Universiteit Leiden
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: General inclusion criteria include age between 3 and 6 years old, voluntary participation, Dutch or English speaking and a signed informed consent from parents or official caretakers. For the ASD groups additional inclusion criteria are an independent clinical diagnosis of autism according to the DSM-IV criteria that will be confirmed with an ADI-R and ADOS at the start of this study, intelligence quotient above 50, no neurological condition (i.e. epilepsy), severe head trauma with loss of consciousness and / or metabolic diseases.
Exclusion criteria
Exclusion criteria: General exclusion criteria are: - IQ
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study outcome is the change in overall functioning of children with ASD, due to the PRT intervention, as expressed in scores on questionnaires and behavioral observations. We aim to predict these changes in overall functioning from child and parent characteristics on three different measurement levels. Physiological measures, as expressed in heart rate, skin conductance, and salivary cortisol. Cognitive measures, as expressed in intellectual functioning, social cognition, language and executive functioning. And finally, involving behavioral measures as expressed in questionnaires and behavioral observations. For a detailed overview on all the study parameters (categorized by measurement level and by child- or parent characteristics), and their abbreviations, see Table 3 of the research protocol. | — |
Secondary
| Measure | Time frame |
|---|---|
| Child*s background information: The parent will fill in a questionnaire concerning overall psychopathology (CBCL). This questionnaire will be used as a categorical screener for general problem behavior that might cause or mask differences on variables of interest and therefore need to be controlled for. Parent*s background information: Parents will fill in a questionnaire concerning their motivation for their present situation to change (PMI). In addition a psychiatric structured interview will be administered with mother (MINI-plus) to screen for possible overall psychopathology. | — |
Countries
Netherlands
Outcome results
None listed