What should be done in women with an incomplete evacuation of the uterus after treatment with misoprostol for miscarriage? An analysis of costs and effects.

What should be done in women with an incomplete evacuation of the uterus after treatment with misoprostol for miscarriage? An analysis of costs and effects. - MisoREST

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON39356

Enrollment

162

Registered

2012-02-14

Start date

2012-07-04

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

miscarriage retained products of conception

Interventions

Curettage versus expectant management.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with a miscarriage treated with misoprostol, and sonographic evidence of remnant of the miscarriage at the follow-up visit 7 days after initial treatment.

Exclusion criteria

Exclusion criteria: Women aged below 18 years Women with severe vaginal bleeding Women with severe abdominal pain Women with fever (> 38.0) or sepsis requiring antibiotic treatment and curettage, Women with contraindications for curettage Women with a failed misoprostol-induced miscarriage, as substantiated by the sonographic finding of an intact gestational sac still in situ.

Design outcomes

Primary

Measure	Time frame
The primary outcome is the success rate in reaching an empty uterus, as substantiated by normal sonographic findings.	—

Secondary

Measure	Time frame
Secondary outcomes are Quality of Life scores assessed with the SF-36, the need of additional treatments, complications, quality of recovery pain and costs.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)