Long term functional outcome, quality of life, and genetic factors in patients with a cloacal malformation

Long term functional outcome, quality of life, and genetic factors in patients with a cloacal malformation - Cloaca: functional outcome, quality of life, and genetic factors

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39349

Enrollment

Registered

2013-09-09

Start date

2013-01-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital fusion of rectum urogenital sinus with a rectovaginal fistula vagina and urethra

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patiënt is born with a cloacal malformation Patiënt is born after 1984 and before 2006

Exclusion criteria

Exclusion criteria: Patient is lost in follow-up

Design outcomes

Primary

Measure	Time frame
Primary outcome of the study are the scores from the completed questionnaires, the results from the urologic tests, the results from the gynecological consult and the MRI-study, laboratory results from urine and blood samples, and the results from the genetic tests.	—

Secondary

Measure	Time frame
The results from the questionnaires indicate colorectal function, urological function, gynecological function and sexual functioning. The two days voiding chart diary and the results from the urological tests both indicate bladder function. Laboratory results show the presence of any (chronic) inflammation of the urinary tract. Gynecological consult outcome as well as results from the MRI study will indicate gynecological and sexual function and will give information about fertility status. Laboratory results from the blood sample tests will indicate renal function. Genetic test results will show any genetic mutations that may play a role in the origination as well as the inheritability of cloacal malformations.	—

Measure

Time frame

The results from the questionnaires indicate colorectal function, urological function, gynecological function and sexual functioning. The two days voiding chart diary and the results from the urological tests both indicate bladder function. Laboratory results show the presence of any (chronic) inflammation of the urinary tract. Gynecological consult outcome as well as results from the MRI study will indicate gynecological and sexual function and will give information about fertility status. Laboratory results from the blood sample tests will indicate renal function. Genetic test results will show any genetic mutations that may play a role in the origination as well as the inheritability of cloacal malformations.

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Countries

Netherlands

Outcome results