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A randomized controlled trial to evaluate the effectiveness and cost-effectiveness of exercise interventions after chemotherapy on physical fitness, fatigue and quality of life.

A randomized controlled trial to evaluate the effectiveness and cost-effectiveness of exercise interventions after chemotherapy on physical fitness, fatigue and quality of life. - REACT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON39339
Enrollment
280
Registered
2010-10-14
Start date
2011-03-25
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer cervix cancer colon cancer ovarian cancer testis cancer or lymphomas cancer

Interventions

A. High intensity exercise program Patients allocated to the high intensity exercise program will train in groups twice a week for 12 weeks under supervision of a physiotherapist. One training sess

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with histological confirmed primary breast, colon, ovarian, cervix, testis cancer or lymphomas with no indication of recurrent or progressive disease, who completed ((neo)adjuvant) chemotherapy with curative intention, are eligible for this study.

Exclusion criteria

Exclusion criteria: Patients who are not able to perform basic activities such as walking or biking, who show cognitive disorders or severe emotional instability, who are suffering from other disabling comorbidity that might hamper physical performance capacity ( e.g. heart failure, chronic obstructive pulmonary disease (COPD), orthopaedic conditions and neurological disorders), and patients who are unable to understand and read the Dutch language will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
Cardiorespiratory fitness, muscle strength and fatigue.

Secondary

MeasureTime frame
Secondary outcome variables include body composition and bone mineral density, health-related quality of life, physical activity level, satisfaction with the intervention, mood disturbances, sleep quality, functioning in daily life and return to work.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)