Blood Platelet Function During and After Liver Resection; an observational study

Blood Platelet Function During and After Liver Resection; an observational study - Blood Platelet Function During and After Liver Resection

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39312

Enrollment

Registered

2011-11-11

Start date

2012-01-13

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver tumors malign or benign liver tumor(s) including distant metastasis to the liver

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Sutdy group: (extended) right hemi-hepatectomy for a malign or benign tumor including distant metastasis the liver For the control group: pylorus preserving pancreaticoduodenectomy for pancreas head cancer.

Exclusion criteria

Exclusion criteria: 1) age: patients younger than 18 and older than 65 years of age; 2) patients who use (selective)serotonin reuptake inhibitors (SSRI); 3) patients with arterial thrombosis in their medical history; 4) patients who use anticoagulants such as vitamin K antagonists, aspirin, and plavix; 5) patients with liver cirrhosis.

Design outcomes

Primary

Measure	Time frame
In this study we will examine at different timepoints during or after a liver resection or a PPPD: a) the activation status of platelets b) platelet activatability c) the content of platelet granules, and d)t he activation of de novo synthesis of mitogenic proteins.	—

Countries

Netherlands

Outcome results