The influence of perioperative myocardial ischemia on postoperative complications in abdominal surgical patients at risk for coronary artery disease.

The influence of perioperative myocardial ischemia on postoperative complications in abdominal surgical patients at risk for coronary artery disease. - Myocardial ischemia and postoperative complications.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39296

Enrollment

196

Registered

2012-05-24

Start date

2012-06-07

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

angina myocardial ischemia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients > 45 years of age with 1 or more major cardiovascular risk factors: Congestive heart failure, peripheral artery disease (intermittent claudication, history of vascular surgery etc), diabetes mellitus type I or II, coronary artery disease (history of myocardial infarction, stable angina pectoris, history of ischemia or coronary artery disease on cardiac tests (ECG, scintigraphy, echocardiogram, coronairangiogram etc), CVA, renal insufficiency (creat > 150umol/l), aortic valve stenosis (valve area 70, hypertension, high cholesterol, low functional capacity (4 METs or less), TIA, COPD AND undergoing abdominal surgery with an expected 30-day mortality rate > 2-3%: colorectal, gastric, pancreatic and liver surgery.

Exclusion criteria

Exclusion criteria: Age

Design outcomes

Primary

Measure	Time frame
Perioperative myocardial ischemia characterized by positive high sensitive cardiac troponin T tests at day 0, 1, 3, 7. To rule out an increase in troponin T due to inflammation an IL-6 and TNF-A determination will be performed in in all samples.	—

Secondary

Measure	Time frame
Fatal and nonfatal postoperative complications: death, wound infection, sepsis, CVA/TIA, heart failure, AF, anastomotic dehiscence, respiratory insufficiency during 30 days after the surgical procedure.	—

Countries

Netherlands

Outcome results