Assess the total set of mechanical loads and mechanical properties of vessel wall and plaque constituents involved in plaque rupture

Assess the total set of mechanical loads and mechanical properties of vessel wall and plaque constituents involved in plaque rupture - Assessment of mechanical properties of the carotid atherosclerotic plaque

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39249

Enrollment

104

Registered

2010-10-19

Start date

2012-06-01

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atherosclerose vessel occlusion

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: age > 60, symptomatic and asymptomatic patient are both necessary for this research, Candidate for endarterectomy of carotid artery, > 70% stenosis

Exclusion criteria

Exclusion criteria: Unable to give written informed consent Obstructed carotid arteries Assymetric EEG

Design outcomes

Primary

Measure	Time frame
Investigation of the mechanical properties of the plaque and underlying vessel wall ex vivo. Determination of the plaque geometry. Determination of the deformation of the plaque.	—

Secondary

Measure	Time frame
Correlation of 3D ultrasound in vivo with ex vivo ultrasound and histology.	—

Countries

Netherlands

Outcome results