Gastrointestinal Ischemia in Acute and Chronic Portal Vein Thrombosis

Gastrointestinal Ischemia in Acute and Chronic Portal Vein Thrombosis - Ischemia and Portal Vein Thrombosis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39226

Enrollment

Registered

2008-12-18

Start date

2009-02-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

portal vein obstruction thrombosis of the portal vein

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Unambiguous evidence of complete thrombosis of the main portal vein (endoluminal material and absence of flow or presence of cavernous transformation), as detected by proper imaging techniques (duplex ultrasound, computerised tomography (CT), magnetic resonance imaging (MRI) or venography). - Date of diagnosis after 01-01-2000 - Age >18 years - Signed informed consent;Controlgroup: - >18 years - Signed informed consent - Patients with liver corrhosis and portal hypertension - Patent mesentery arteries and veins

Exclusion criteria

Exclusion criteria: - Liver cirrhosis - Malignancy - No informed consent - Pregnant or lactating women;Controlgroup: -

Design outcomes

Primary

Measure	Time frame
The prevalence of gastrointestinal ischemia in patients with non-cirrhotic, non-malignant PVT.	—

Secondary

Measure	Time frame
- Evaluation of cardiovascular risk factors - Evaluation of small bowel function using a sugar-absorption test (SAT) - Comparison of visible light spectroscopy with findings at duplex ultrasound examination - Prevalence of gastrointestinal ischemia in patients with acute and chronic PVT - Prevalence of gastrointestinal ischemia in patients with an extended thrombosis of the portal vein (i.e. additional thrombosis of the superior mesenteric vein), as detected by duplex ultrasound - Relationship between diagnosis of gastrointestinal ischemia and symptoms - Comparison of mucosal saturation measurements using VLS between patients with PVT and patients with liver cirrhosis and portal hypertension with patent mesentery arteries and veins	—

Measure

Time frame

- Evaluation of cardiovascular risk factors - Evaluation of small bowel function using a sugar-absorption test (SAT) - Comparison of visible light spectroscopy with findings at duplex ultrasound examination - Prevalence of gastrointestinal ischemia in patients with acute and chronic PVT - Prevalence of gastrointestinal ischemia in patients with an extended thrombosis of the portal vein (i.e. additional thrombosis of the superior mesenteric vein), as detected by duplex ultrasound - Relationship between diagnosis of gastrointestinal ischemia and symptoms - Comparison of mucosal saturation measurements using VLS between patients with PVT and patients with liver cirrhosis and portal hypertension with patent mesentery arteries and veins

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Countries

Netherlands

Outcome results