Corneal transplantation by ultra-thin DSAEK: thinner grafts, better vision?

Corneal transplantation by ultra-thin DSAEK: thinner grafts, better vision? - Ultra-thin DSAEK study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON39225

Enrollment

Registered

2012-01-23

Start date

2013-06-05

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal endothelial failure

Interventions

The intervention consists of the performance of standard DSAEK (grafts of approximately 200 microns) or ultra-thin DSAEK (grafts of approximately 75 microns).

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Endothelial dysfunction caused by pseudophakic or aphakic corneal edema, (Fuchs*) endothelial dystrophy, a minimum patient age of 18 years, and best spectacle-corrected visual acuity (BSCVA) lower than 20/50.

Exclusion criteria

Exclusion criteria: Previous corneal transplantation, human leukocyte antigen typed keratoplasty, and patients who are unable to communicate properly or to understand instructions.

Design outcomes

Primary

Measure	Time frame
Primary outcome measure is best corrected visual acuity.	—

Secondary

Measure	Time frame
Secondary outcome measures are contrast acuity, astigmatism, quality of vision, endothelial cell loss, incidence of graft rejection, primary graft failure, cornea donor loss due to preparation, and generic and vision-related quality of life.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)