Effect of optical density filters on retinal nerve fiber layer and macular inner retinal layer thickness measurements using spectral domain optical coherence tomography

Effect of optical density filters on retinal nerve fiber layer and macular inner retinal layer thickness measurements using spectral domain optical coherence tomography - OCT image quality

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39167

Enrollment

Registered

2012-07-25

Start date

2013-10-23

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oogaandoeningen, staar glaucoma ocular hypertension

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria healthy volunteers * Willing and able to sign the informed consent, after reading the information form * No history of ophthalmological disease;Glaucoma patients: * Willing and able to sign the informed consent, after reading the information form * Diagnosed with primary open angle glaucoma;Cataract patients: * Willing and able to sign the informed consent, after reading the information form * Diagnosed with cataract and eligible for cataract surgery

Exclusion criteria

Exclusion criteria: For healthy volunteers and glaucoma patients * Media opacities, like cataract, that will make it impossible to make reliable images with the OCT * Hypermetropia more than S+5 dioptres, or myopia more than S-8 dioptres * Presence of diseases including retinal disorders that may influence visual acuity, visual field testing or the results of structural measurements done by SD-OCT;For cataract patients: * Media opacities other than cataract, that will make it impossible to make reliable images with the OCT * Hypermetropia more than S+5 dioptres, or myopia more than S-8 dioptres * Presence of other diseases including retinal disorders that may influence visual acuity, visual field testing or the results of structural measurements done by SD-OCT

Design outcomes

Primary

Measure	Time frame
The amount of measured layer thickness decrease in retinal layer thickness measurements, induced by the increase in optical density of the artificial filters. The relationship between the underestimation of the retinal layer thicknesses and the optical density of the artificial filters. The relationship between these filter measurements before and after cataract surgery. The difference in measured RNFL thickness between volume scans and peripapillary circle scans of the optic nerve head.	—

Measure

Time frame

The amount of measured layer thickness decrease in retinal layer thickness measurements, induced by the increase in optical density of the artificial filters. The relationship between the underestimation of the retinal layer thicknesses and the optical density of the artificial filters. The relationship between these filter measurements before and after cataract surgery. The difference in measured RNFL thickness between volume scans and peripapillary circle scans of the optic nerve head.

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Countries

Netherlands

Outcome results