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Analysis of expression differences between endometria of women with PCOS and normal cycling women, collection of normal endometrial tissue

Analysis of expression differences between endometria of women with PCOS and normal cycling women, collection of normal endometrial tissue - Genexpression profiles of endometria of PCOS women

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON39161
Enrollment
10
Registered
2010-04-15
Start date
2010-10-01
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovary syndrom

Interventions

None listed

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Regular menstrual cycle (between 25 and 35 days) - BMI >18 and

Exclusion criteria

Exclusion criteria: Women which are diagnosed with endometriosis (based on clinical findings, questionair, gynaecological examination, transvaginal ultrasound or laparoscopy).

Design outcomes

Primary

MeasureTime frame
- Determine endometrial gene-expression profiles from women with a normal regular cycle and from PCOS women - Determine basal levels for E2, LH, FSH, AMH, prolactin, free testosterone, SHBG, DHEA-S, and 17-hydroxyprogesterone (17-OHP) of control patients and PCOS patients - Identify endometrial genes and pathways contributing to PCOS related infertility.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)