Minimal invasive imaging of coronary artery disease in patients with asymptomatic myocardial injury after major non-cardiac surgery.

Minimal invasive imaging of coronary artery disease in patients with asymptomatic myocardial injury after major non-cardiac surgery. - Asymptomatic myocardial injury after non-cardiac surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39130

Enrollment

Registered

2012-03-26

Start date

2012-09-05

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial damage

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Major non-cardiac surgery with > 2 overnight stay Troponin elevation post-operatively: > 0.01 ng/ml Age > 60 year No clinical signs of myocardial ischemia

Exclusion criteria

Exclusion criteria: Hemodynamic instability Contra-indication for MRI e.g.metal prosthesis Previous myocardial infarction Severe renal failure: GFR

Design outcomes

Primary

Measure	Time frame
Main study parameters: 1. Coronary artery disease with luminal narrowing > 50 % in one or more major epicardial vessels by CT 2. Presence and extent of coronary artery atherosclerosis as measured with coronary CT 3. Minimal myocardial injury measured by late gadolinium enhancement on MRI 4) Myocardial ischemia on adenosin perfuion MRI	—

Secondary

Measure	Time frame
Secondary study parameter: Agatston coronary calcium score.	—

Countries

Netherlands

Outcome results