Uremic Toxins, Cardiovascular Effects and Physical Activity in Intensive Hemodialysis

Uremic Toxins, Cardiovascular Effects and Physical Activity in Intensive Hemodialysis - Long-term Effects of Intensive Hemodialysis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39123

Enrollment

140

Registered

2011-04-27

Start date

2012-08-31

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

end-stage renal disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: -Incident and prevalent conventional hemodialysis (CHD), intensive HD [short daily hemodialysis (SDHD), nocturnal hemodialysis (NHD) and home nocturnal hemodialysis (HNHD)] and peritoneal dialysis (PD) patients -Different patient groups (CHD, intensive HD and PD) will be matched according to transplantation candidature en Charlson Comorbidity Index -Standard renal diet (80 g of protein per day) -Age > 18 years -Informed consent

Exclusion criteria

Exclusion criteria: -Charlson risk index of 5 or higher -Chronic antibiotic use and colectomy because of interference with uremic toxin formation and degradation -Withdrawal of consent -For bio-impedance measurements: presence of ICD or pacemaker. There are no restrictions for other measurements in these patients.

Design outcomes

Primary

Measure	Time frame
-Pulse wave velocity	—

Secondary

Measure	Time frame
-Levels of uremic toxins -Physical activity	—

Countries

Netherlands

Outcome results