Comparison of Left and Right Ventricular Geometry and Functional Parameters in Chronic Fatigue Syndrome Patients versus Age- and Sex- Matched Healthy Controls Assessed by Cardiovascular Magnetic Resonance Imaging.

Comparison of Left and Right Ventricular Geometry and Functional Parameters in Chronic Fatigue Syndrome Patients versus Age- and Sex- Matched Healthy Controls Assessed by Cardiovascular Magnetic Resonance Imaging. - Normal values of Left and Right ventricular dimensions by CMR imaging

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39100

Enrollment

Registered

2010-10-18

Start date

2010-11-24

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chamber function heart function

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy female volunteers, age range 20-60 years. Able to provide informed consent.

Exclusion criteria

Exclusion criteria: Previous cardiovascular disease known diseases with cardiac involvement Unwillingness to use or contra-indications for contrast agents Age 60 years Pregnancy Breast feeding Kidney dysfunction Body mass index > 30 Claustrophobia or other exclusion criteria for MRI such as implanted metal materials

Design outcomes

Primary

Measure	Time frame
The main study parameters will be LV and RV geometry and function (i.e., LV and RV end-diastolic volume, end-systolic volume, end-diastolic wall mass, wall motion score and ejection fraction) and tissue characterization of the myocardium, to assess presence and extent of CE.	—

Secondary

Measure	Time frame
To assess the level of activity* in the healthy female volunteers in order to correspond with the physically inactive CFS population and to assess if small expected differences in LV/RV geometry, function and tissue characterization in the female healthy subgroup can be explained by individual level of activity. * The level of activity in the individual healthy volunteers is quantitatively determined by (1) using a validated questionnaire and (2) completing a bicycle exercise test.	—

Measure

Time frame

To assess the level of activity* in the healthy female volunteers in order to correspond with the physically inactive CFS population and to assess if small expected differences in LV/RV geometry, function and tissue characterization in the female healthy subgroup can be explained by individual level of activity. * The level of activity in the individual healthy volunteers is quantitatively determined by (1) using a validated questionnaire and (2) completing a bicycle exercise test.

—

Countries

Netherlands

Outcome results