psychotic disorders
Conditions
Interventions
Admission of a single dose of Sinemet
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: All patients will be recruited from the Psychiatry ward of the Erasmus Medical Center, Rotterdam, and diagnosed according to DSM-IV criteria by a senior psychiatrist Patients will be included if they meet the criteria for schizophrenia. Further inclusion criteria inpatients aged 18-35 years with a diagnosis of schizophrenia, stable on antipsychotic, with illness duration < 5 years
Exclusion criteria
Exclusion criteria: pregnancy, use of psychotropic medication other than benzodiazepines, serious neurological disorders. Subjects will also be excluded when they cannot understand Dutch language sufficiently to understand the purposes and implications of the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive functioning as assessed by a habit formation task and a n-back working memory task | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical variables as measured by a panss interview and two questionnaires | — |
Countries
Netherlands
Outcome results
None listed