Risk calculation for Pre-Eclampsie and Grwoth Restriction in the First Trimester

Risk calculation for Pre-Eclampsie and Grwoth Restriction in the First Trimester - PERC - Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39085

Enrollment

3000

Registered

2013-11-14

Start date

2014-06-09

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre-eclampsia - New-onset Hypertension and Proteinuria in Pregnancy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Primigravida Viable singleton pregnancy

Exclusion criteria

Exclusion criteria: Minors (being under the age of 18) Incapacitated persons Not mastering the Dutch language

Design outcomes

Primary

Measure	Time frame
The main objective of the study is to evaluate the performance of two existing algorithms for the prediction of PE and growth restriction not associated with PE. These algorithms (including the following variables: ethnicity, body mass index (BMI), mean arterial pressure (MAP), lowest Doppler resistance measurement (PI) of both uterine arteries and maternal serum blood markers (PAPP-A and PLGF)) will be tested and other possible combinations of variables will be evaluated for their predictive ability.	—

Measure

Time frame

The main objective of the study is to evaluate the performance of two existing algorithms for the prediction of PE and growth restriction not associated with PE. These algorithms (including the following variables: ethnicity, body mass index (BMI), mean arterial pressure (MAP), lowest Doppler resistance measurement (PI) of both uterine arteries and maternal serum blood markers (PAPP-A and PLGF)) will be tested and other possible combinations of variables will be evaluated for their predictive ability.

—

Secondary

Measure	Time frame
Secondary objectives: - Evaluating the learning curve for measurement of the uterine arteries - Inter and intra- observer variation of measurement of the uterine arteries - Quality assessment of the measurements of the uterine arteries - Time needed to collect informed consent, maternal history and measurement of the maternal blood pressure and uterine arteries	—

Countries

Netherlands

Outcome results