myopathy. Vitamin D hypovitaminose
Conditions
Interventions
This study is a randomised two-arm trial of vitamin D supplementation with
Vitamin D Intensive Outreach (VIDIO) including cholecalciferol loading dose, if
applicable, and subsequent (bimonthly) high
Sponsors
Korsakovcentrum Slingedael
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria are having a history of alcohol abuse and currently living in Rotterdam and vicinity, and serum 25-hydroxyvitamin D concentration below 50 nmol/L at baseline.
Exclusion criteria
Exclusion criteria: Exclusion criteria are a high risk or serious suspicion of Wernicke*s encephalopathy, knee surgery, first year after hip surgery, pregnancy/lactating or trying to conceive, already having vitamin D prescriptions for treatment of osteoporosis or hypo-vitaminosis D myopathy, inability to give informed consent because of mental incapacity, insufficient command of the Dutch language, and contraindications of Calci Chew D3 or cholecalciferol: hypercalcaemia, renal failure (glomerular filtration rate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcomes are serum 25(OH)D concentrations. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes include the participants* quadriceps maximal voluntary contractions, gait and balance abilities, and a health-related quality of life evaluation. | — |
Countries
Netherlands
Outcome results
None listed