Feasibility of using the Pap-smear as a screening device for the detection of endometrial and ovarian cancer

Feasibility of using the Pap-smear as a screening device for the detection of endometrial and ovarian cancer - Detecting endometrial and ovarian cancer with the Pap-smear

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON39020

Enrollment

150

Registered

2013-11-29

Start date

2014-03-11

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical smear (Pap-smear) uterine cancer (endometrial cancer)

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Endometrial cancer: patient suspected of having endometrial cancer i.e. postmenopausal bleeding Ovarian cancer: patient highly (99% certainty) suspected of having ovarian cancer. This will be based on RMI>200, CA125/CEA ratio, ascites, peritoneal depositions, omental cake or even laparoscopic evaluation.

Exclusion criteria

Exclusion criteria: Previous pelvic radiotherapy

Design outcomes

Primary

Measure	Time frame
The main study parameter is the correlation between mutations found in the Pap-smear and the pipelle endometrial sampling and the primary tumor.	—

Secondary

Measure	Time frame
The main study parameter is the correlation between mutations found in the vaginal swab and the pipelle endometrial sampling and the primary tumor. To assess the correlation between the results of the mutation analysis and tumour characteristics (histology, stage).	—

Countries

Netherlands

Outcome results