high blood pressure oxidative stress
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Individual is accepted for treatment with renal denervation as standard therapy for resistant hypertension. 2. Individual is *18 years of age. 3.Individual agrees to have all study procedures performed, and is competent and willing to provide written informed consent to participate in this clinical study.
Exclusion criteria
Exclusion criteria: 1. Individual is excluded from treatment with pRDN. 2. Individual has an estimated glomerular filtration rate (eGFR) of
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effect of renal denervation on markers of oxidative stress present in blood, urine and isolated leukocytes. | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine whether blood pressure, insulin resistance, kidney function and lipid profile are related to ROS production. | — |
Countries
Netherlands
Outcome results
None listed