The effect of maltitol sweetened chewing gum on the oral microbiology.

The effect of maltitol sweetened chewing gum on the oral microbiology. - Effect of maltitol sweetened chewing gum on the oral microbiology.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON38887

Enrollment

150

Registered

2013-09-06

Start date

2013-09-12

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Microbiologie van de supragingivale tandplaque Oral microbiology and supragingival dental plaque

Interventions

Intervention= maltitol sweetened chewing gum. 3x daily 2 maltitol gums Placebo= gum base. 3 x daily 1 gum Control= no gum

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Male and female - Age *18 years - Classified as systemically healthy, assessed by medical questionnaire - Non-smokers - Minimum of 20 natural teeth: at least 5 evaluable teeth in each quadrant - DPSI 0-3- - With moderate gingivitis (30-60% BOMP) - No partial dentures - No orthodontic banding - No oral lesions - Subjects who do not use a interdental device at home. - No use of antibiotics 60 days before baseline - No pregnancy/breast feeding - No participation in clinical trials 30 days before baseline - No consumer of > 3 sugar free chewing gums a day - Willing and able to give written informed consent - No medication except for birth control pills

Exclusion criteria

Exclusion criteria: - Anyone presenting with a probing depth * 5mm with bleeding on probing and attachment loss * 2 mm - Overt dental caries - Usage of any interdental device as part of regular daily oral care - Smokers - DPSI 3+-4 - Removable (partial) dentures - Crowns, bridges and implant supported restorations - Removable night guard - Oral and/or peri-oral piercings - Apparent oral lesions (aphthous ulcers excluded) - Presence of orthodontic banding (except for lingual retention wire) - Dental student or dental professional - Participation in a clinical study within the previous 30 days ;General health and use of medication: - Self-reported pregnancy or breastfeeding - Use of antibiotics during the last 2 months - Need of antibiotic prophylaxis prior to dental treatment - Use of anti-inflammatory drugs on a regular basis - Evidence of any systemic disease or compromised health condition - Adverse medical history or long-term medication - Prescribed medication (except for birthcontrol pills)

Design outcomes

Primary

Measure	Time frame
2 Supra gingival plaque samples	—

Secondary

Measure	Time frame
Food questionnaire	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)